Chapter 3
Potential for Increased Investment Activity in 2025
U.S. Life Sciences Outlook 2025
2 Minute Read
2 Minute Read
Sales transactions of life sciences lab/R&D properties hit their lowest level in over a decade in 2024, largely due to high interest rates and weak supply-and-demand fundamentals.
CBRE Research projects marginally higher investment sales in 2025 for all commercial real estate sectors based on improved macroeconomic trends, lower interest rates and greater demand. Life sciences investment activity may see a slight uptick, although the sector’s surge in new supply in H1 2025 will be a headwind.
Figure 28: Annual Investment Volume of R&D Properties
While conventional office properties have seen cap rates jump to levels not seen in over a decade, cap rates for life sciences properties appeared to stabilize in 2024 and remained below levels a decade ago.
CBRE expects the 10-year Treasury yield to remain above 4% in 2025, suggesting that any potential decline in life sciences cap rates will be marginal.
Figure 29: Average Cap Rates for Office and R&D Properties
Related Insights
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Despite many uncertainties, the U.S. economy is poised for growth in 2025, driven by consumer spending, easing financial conditions and productivity gains.
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Companies have many ways to prepare life sciences real estate portfolios for AI’s future requirements, while maintaining flexibility in the interim.
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Press Release
ZA Secures Top Four Floors of Tower 3, Lee Garden Eight for New Headquarters
September 9, 2026
CBRE has successfully advised ZA, the parent company of Hong Kong’s first digital bank, ZA Bank, on the leasing of approximately 44,000 sq. ft. across the top four floors of Tower 3 at Lee Garden Eight, the newest Grade A office development, by Hysan Development and Chinachem Group in Causeway Bay, scheduled for completion by the end of 2026.
